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1.
What is vertebroplasty?
2. What is a compression
fracture?
3. What causes
vertebral body compression fractures?
4. What are the
possible residual effects of a vertebral fracture?
5. What are the
leading causes of osteoporosis?
6. Who are the
best candidates for vertebroplasty?
7. How should I
prepare for the procedure?
8. What does the
equipment look like?
9. How does the
procedure work?
10. How is the
procedure performed?
11. What will
I experience during the procedure?
12. What happens
after the procedure?
13. What is the
cost of vertebroplasty?
14. What are the
benefits vs. risks?
15. What are the
limitations of vertebroplasty?
What is Vertebroplasty?
Traditionally,
vertebral fractures have been treated with analgesics, braces and
bed rest. Methods such as these have proven to be ineffective. Percutaneous
vertebroplasty is a minimally invasive procedure which has demonstrated
highly successful outcomes. Vertebroplasty is an image-guided, non-surgical
therapy used to strengthen a broken vertebra (spinal bone) that
has been weakened by osteoporosis or, less commonly, cancer. Vertebroplasty
can increase the patient's functional abilities, allow a return
to the previous level of activity, and prevent further vertebral
collapse. It is usually successful at alleviating the pain caused
by a compression fracture. Success rates as high as 90% have been
reported world wide. Often performed on an outpatient basis, vertebroplasty
is accomplished by injecting an orthopedic cement mixture through
a needle into the fractured bone.
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What
is a compression fracture?
Vertebrae
are the bones of the back which join together to make up the spinal
column. In a compression fracture of the vertebrae, the bone tissue
of the vertebral body collapses. More than one vertebra may be affected.
With
multiple fracture skyphosis, a forward hump-like curvature of the
spine may result. Pressure on the spinal cord may occur, producing
symptoms of numbness, tingling or weakness.
Symptoms
depend on the area of the back that is affected. In some cases,
the fracture heals without treatment and the pain goes away. In
others, the bone does not stabilize and continues to move, causing
persistent pain that in turn limits physical activities and reduces
independence.
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What
causes vertebral body compression fractures?
The
leading cause of vertebral body fractures is osteoporosis. Osteoporosis
is a condition where the bone becomes thin and weak, losing valuable
minerals. People may not know that they have osteoporosis until
their bones become so weak that a sudden strain, bump or fall causes
a fracture or a vertebra to collapse causing significant pain and
subsequently, the loss of movement. An estimated ten million people
in the United States suffer from osteoporosis according to the National
Osteoporosis Foundation.
Osteoporosis
currently accounts for more than 1.5 million fractures a year, 700,000
of which are vertebral compression fractures. The majority of these
include fractures due to the use of steroids used to treat asthma,
lupus and rheumatoid arthritis. The loss of bone and minerals causes
the bone to become so weak that a simple cough, sneeze or sudden
movement can cause a vertebral fracture. When the fracture occurs
as the result of osteoporosis, the vertebrae in the thoracic (chest)
and lower spine are usually affected and symptoms may become worse
with walking.
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What
are the possible residual effects of a vertebral fracture?
The
chronic back pain associated with a vertebral fracture severely
inhibits the patient's way of life. The patients are often bed-ridden
and forced to depend on others for everyday activities. Other effects
can be decreased lung capacity, loss of appetite and malnutrition.
Increased morbidity rates and sleeping disorders have also been
proven to be associated with vertebral fractures. Each of these
also may lead to other disorders as well.
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What
are the leading causes of osteoporosis?
The
following factors will increase the likelihood of acquiring osteoporosis:
· Thin or underweight
· Elderly
· Low calcium intake
· Eating disorders
· Family history of osteoporosis
· Female
· Steroid use
· Post menopausal
· Smoking
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Who
are the best candidates for vertebroplasty?
People
who have experienced vertebral fractures causing moderate to severe
back pain despite conservative therapy such as bed rest and pain
relieving medications are the primary candidates for this procedure.
Vertebral fractures are best treated the earlier they are diagnosed.
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How
should I prepare for the procedure?
First,
you will be clinically examined. The evaluation generally includes
diagnostic imaging, blood tests and a physical exam. Diagnostic
imaging such as spine x-rays, a radioisotope bone scan or magnetic
resonance imaging (MRI) will be done to confirm the presence of
a compression fracture that is amenable to vertebroplasty. If an
MRI cannot be performed because of a pacemaker or other medical
factor, a CT scan can be substituted. In preparation for the clinical
evaluation and physical exam, you should obtain and bring with you
any previous diagnostic images, especially x-rays or MRI films.
Notify your physician of your current medications including your
daily dosages and of any allergies to medications, current infections,
high blood pressure, diabetes, asthma or any other abnormal conditions.
Be sure to tell your doctor if you are allergic to x-ray contrast
material, which contains iodine.
Pre-procedure
instructions: Do not eat for at least six hours before the procedure.
If you are diabetic, you should contact your doctor for instructions
on regulating your blood sugar and medications. On the day of the
procedure, if your doctor instructs you to take your usual medications,
swallow your medication with sips of water or clear liquid up to
three hours before the procedure. Avoid drinking orange juice, cream
and milk.
If
you take an anti-coagulation medication (blood thinners such as
Coumadin), you will have to stop the treatment until coagulation
becomes normal, usually within three to five days. Do not take any
aspirin or aspirin containing products (such as Alka-Seltzer or
Pepto-Bismol) for five days before your procedure. Do not take any
herbal remedies, such as ginkgo biloba, for five days prior to your
procedure. Do not take NSAIDs (ibuprofen) for three days prior to
your procedure. Contact your doctor before stopping any medication
to determine if it is safe for you. All patients should arrange
for an adult to drive them home after the procedure.
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What
does the equipment look like?
A
hollow needle (trocar) is passed into the vertebral bone and a cement
mixture including polymethylmethacrylate (PMMA), barium powder and
a solvent is injected. The cement mixture resembles toothpaste or
epoxy. The physician will monitor the entire procedure on a fluoroscopy
imaging screen and make sure that the cement mixture does not back
up into the spinal canal.
Sedation
medication will be administered through an intravenous catheter.
You will be attached to the equipment that monitors your heart beat
and blood pressure throughout the procedure.
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How
does the procedure work?
Vertebroplasty
is highly effective because after osteoporosis has made bones very
porous, the cement fills the spaces and strengthens the bone so
it is less likely to fracture again. After vertebroplasty, the cement
stabilizes the fracture, which is thought to provide pain relief.
Patients begin regaining mobility within 24 hours and are usually
able to reduce, or even eliminate, their pain medication.
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How
is the procedure performed?
Vertebroplasty
is generally performed in the morning. You will be sedated and receive
a local anesthetic to numb the skin and the muscles near the spinal
fracture. Intravenous antibiotics may also be administered to prevent
infection. Through a small incision and guided by a fluoroscope,
a hollow needle is passed though the spinal muscles until its tip
is precisely positioned within the fractured vertebra. Once the
needle is shown to be in the proper location, the orthopedic cement
is injected. Medical-grade cement hardens quickly over the next
10-20 minutes. The longest part of the vertebroplasty involves setting
up the equipment and making sure the needle is perfectly positioned
in the collapsed vertebra.
Vertebroplasty
usually takes less than one hour (longer if more than one site is
being treated). Although you will not be allowed to drive after
the procedure, you can go home with an adult.
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What
will I experience during the procedure?
You
will be lying face down throughout the procedure. Sedation medications
will help you stay calm and minimize any discomfort you might feel
during the vertebroplasty. You will be conscious, though drowsy,
and able to hear anything that is said in the room. During the procedure
you will be asked questions such as "Does this hurt?"
It is important for you to be able to tell your doctor whether you
are feeling any pain. Because of the position you will be in, you
will not be able to see the image on the fluoroscope.
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What
happens after the procedure?
Your
physician will instruct you on specific post-procedure recommendations
and offer consultation on recovery following your procedure. Most
patients are able to bear weight very soon after vertebroplasty.
They can get up to walk after resting in bed for about an hour.
Patients may have liquids if no nausea is experienced and may advance
to regular diet if liquids are tolerated. The patient may be discharged
with an adult approximately two hours after the procedure if recovery
is uneventful.
For
two or three days afterward, you may feel a bit sore at the point
of the needle insertion. You can use an icepack to relieve any discomfort
but be sure to protect your skin from the ice with a cloth; use
the pack for only 15 minutes per hour. The tiny incision will be
closed with a strip of tape and covered with a bandage that should
remain on for several days. It is important that the injection site
remain clean. You can shower while the bandage is still on.
Rest
is recommended for the first 24 hours following vertebroplasty.
Increase your activity gradually and resume all your regular medications.
If you take blood thinners, check with your doctor, but you may
be able to restart them after the procedure.
Usually,
patients will receive follow-up calls within the first week after
vertebroplasty to check on their progress and answer any questions.
Patients are instructed to call if they experience new back pain,
chest pain, lower extremity weakness or fever over 100 degrees.
The referring physician or primary care provider provides follow-up
care.
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What
is the cost of vertebroplasty?
Vertebroplasty
is covered by Medicare and most other insurance programs. Co-pays
and deductibles will vary based on your specific plan and the Medicare
program for each particular region.
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What
are the benefits vs. risks?
Benefits
·
Because the pain of a compression fracture is alleviated by vertebroplasty,
patients feel significant relief almost immediately. After just
a few weeks, two-thirds of patients are able to lower their doses
of pain medication significantly. Many patients become symptom-free.
· About 75% of patients regain lost mobility and become more
active, which helps combat osteoporosis. After vertebroplasty, patients
who had been immobile can get out of bed, reducing their risk of
pneumonia. Increased activity builds more muscle strength, further
encouraging mobility.
Risks
Usually,
vertebroplasty is a safe and effective procedure.
·
A small amount of orthopedic cement can leak out of the vertebral
body. This does not usually cause a serious problem, unless the
leakage moves into a potentially dangerous location such as the
spinal canal.
· Other possible complications include infection, bleeding,
increased back pain and neurological symptoms such as numbness or
tingling. Paralysis is extremely rare. Sometimes the procedure causes
another fracture in the spine or ribs.
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What are the limitations of Vertebroplasty?
·
Vertebroplasty is not used for herniated discs or arthritic pain.
· Vertebroplasty is not generally recommended for otherwise
healthy younger patients, mostly because there is limited experience
with cement in a vertebral body for longer time periods.
· The procedure cannot serve as a preventive treatment to
help patients with osteoporosis avoid future fractures. It is used
only to repair a known, non-healing compression fracture.
· Vertebroplasty will not correct an osteoporosis-induced
curvature of the spine, but it may keep the curvature from worsening.
· Patients with a healed vertebral fracture are not candidates
for vertebroplasty.
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